Cardiac amyloidosis: updates in diagnosis and management.

摘要: Amyloidosis is a severe systemic disease. Cardiac involvement may occur in the three main types of amyloidosis (acquired monoclonal light-chain, hereditary transthyretin and senile amyloidosis) has major impact on prognosis. Imaging heart to characterize detect early cardiac one aims assessment this Electrocardiography transthoracic echocardiography are important diagnostic prognostic tools patients with involvement. magnetic resonance imaging better characterizes myocardial involvement, functional abnormalities amyloid deposition due its high spatial resolution. Nuclear role diagnosis cardiomyopathy. biomarkers now used for risk stratification staging light-chain amyloidosis. Different complications occur, including diastolic followed by systolic failure, atrial and/or ventricular arrhythmias, conduction disturbances, embolic events sometimes sudden death. Senile cardiomyopathy have prognoses than treatment failure usually ineffective often poorly tolerated because hypotensive bradycardiac effects. The disease, despite their similar appearance, specific new aetiological treatments that change prognosis Cardiologists should be aware disease allow treatment.