Triplex-forming oligonucleotides as modulators of gene expression.

作者: Ramareddy V Guntaka , Balwantkumar R Varma , Karl T Weber

DOI: 10.1016/S1357-2725(02)00165-6

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摘要: … as well as in the purine and pyrimidine moieties, which … Similar studies using a psoralen-conjugated TFO designed … and p53 mutant human glioblastoma cells with a frequency of …

参考文章(96)
S. K. Swamynathan, Ashok Nambiar, Ramareddy V. Guntaka, Role of single-stranded DNA regions and Y-box proteins in transcriptional regulation of viral and cellular genes The FASEB Journal. ,vol. 12, pp. 515- 522 ,(1998) , 10.1096/FASEBJ.12.7.515
Mehreen Hai, Sanjay I. Bidichandani, Michael E. Hogan, Pragna I. Patel, Competitive binding of triplex-forming oligonucleotides in the two alternate promoters of the PMP22 gene. Antisense & Nucleic Acid Drug Development. ,vol. 11, pp. 233- 246 ,(2001) , 10.1089/108729001317022232
Shawn Ritchie, F.Mark Boyd, Jason Wong, Keith Bonham, Transcription of the human c-Src promoter is dependent on Sp1, a novel pyrimidine binding factor SPy, and can be inhibited by triplex-forming oligonucleotides. Journal of Biological Chemistry. ,vol. 275, pp. 847- 854 ,(2000) , 10.1074/JBC.275.2.847
Paola B. Arimondo, Christian Bailly, Alexandre S. Boutorine, Pascale Moreau, Michelle Prudhomme, Jian-Sheng Sun, Thérèse Garestier, Claude Hélène, Triple helix-forming oligonucleotides conjugated to indolocarbazole poisons direct topoisomerase I-mediated DNA cleavage to a specific site. Bioconjugate Chemistry. ,vol. 12, pp. 501- 509 ,(2001) , 10.1021/BC000162K
Jacob Joseph, Jagan C Kandala, Dange Veerapanane, Karl T Weber, Ramareddy V Guntaka, Antiparallel polypurine phosphorothioate oligonucleotides form stable triplexes with the rat α1(I) collagen gene promoter and inhibit transcription in cultured rat fibroblasts Nucleic Acids Research. ,vol. 25, pp. 2182- 2188 ,(1997) , 10.1093/NAR/25.11.2182
Changxian Shen, Andreas Buck, Gerhard Mehrke, Bülent Polat, Hans-Jügen Gross, Max Bachem, Sven Reske, Triplex forming oligonucleotide targeted to 3′UTR downregulates the expression of the bcl-2 proto-oncogene in HeLa cells Nucleic Acids Research. ,vol. 29, pp. 622- 628 ,(2001) , 10.1093/NAR/29.3.622
Valentina Rapozzi, Susanna Cogoi, Paola Spessotto, Angela Risso, Gian Maria Bonora, Franco Quadrifoglio, Luigi Emilio Xodo, Antigene effect in K562 cells of a PEG-conjugated triplex-forming oligonucleotide targeted to the bcr/abl oncogene Biochemistry. ,vol. 41, pp. 502- 510 ,(2002) , 10.1021/BI011314H
Z. Luo, M. A. Macris, A. F. Faruqi, P. M. Glazer, High-frequency intrachromosomal gene conversion induced by triplex-forming oligonucleotides microinjected into mouse cells Proceedings of the National Academy of Sciences. ,vol. 97, pp. 9003- 9008 ,(2000) , 10.1073/PNAS.160004997
Marcella Faria, Chris D Wood, Mike R.H White, Claude Hélène, Carine Giovannangeli, Transcription inhibition induced by modified triple helix-forming oligonucleotides: a quantitative assay for evaluation in cells11Edited by M. Yaniv Journal of Molecular Biology. ,vol. 306, pp. 15- 24 ,(2001) , 10.1006/JMBI.2000.4386