The Short-Form Leeds Dyspepsia Questionnaire validation study.

摘要: Summary Background Assessment of symptoms should be the primary outcome measure in dyspepsia clinical trials. This requires a reliable, valid and responsive questionnaire that measures frequency severity dyspepsia. The Leeds Dyspepsia Questionnaire fulfils these characteristics, but is long was not designed for self-completion, so shorter developed (the Short-Form Questionnaire). Aim To assess acceptability, interpretability, internal consistency, reliability, validity responsiveness secondary care. Methods Unselected care patients completed Questionnaire. Test–retest reliability assessed after 2 days. Validity measured by comparison with general practitioners’ diagnosis. Sensitivity analysis logistic regression were employed to determine most scoring system. Responsiveness determined before treatment endoscopically proven disease. Results The administered 388 204 patients. Pearson coefficient test–retest 0.93. had sensitivity 77% specificity 75%. A highly significant response change observed (P < 0.005). Conclusions The self-completed quantifying symptoms, which more convenient than