Human leukemia and retroviruses.

作者: Abraham Karpas

DOI: 10.1007/978-1-4899-1675-4_5

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摘要: In 1908 the Danish veterinarians Vilhelm Ellerman and Oluf Bang showed that leukemia in chickens was transmissible by cell-free filtrates therefore presumably caused a virus. This first virus-induced malignancy to be discovered. Then, 1911, Peyton Rous sarcoma could transmitted filtrate, which indicated it due virus; he also pointed out presumptive agent always same type of tumor chick must carry specific genetic information. More recently shown viruses are essentially have transduced cellular oncogenes. so much ahead his time for several decades work kept on shelf Curiosa; not until 1966, when 86 years old, recognized award Nobel Prize had done 55 earlier.

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