Mechanistic studies and radiofluorination of structurally diverse pharmaceuticals with spirocyclic iodonium(III) ylides

作者: Benjamin H. Rotstein , Lu Wang , Richard Y. Liu , Jon Patteson , Eugene E. Kwan

DOI: 10.1039/C6SC00197A

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摘要: … radiolabeled using conventional nucleophilic aromatic substitution with [ 18 F]fluoride. … F–I–C plane, perhaps in part due to a stabilizing hydrogen bond with the basic fluoride. This is the …

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