Helicobacter pylori infection and peptic ulcer disease

摘要: At the stage when peptic ulcers appeared to become clinically controlled by more and potent acid inhibitory agents, traditional concept of ulcer pathogenesis was turned upside down discovery a microorganism specialized infect human gastric mucosa. Helicobacter pylori infection is now recognized as predisposing key factor has assigned contributory though important role in duodenal ulcerogenesis. The this bacterium reopened chapters physiology pathophysiology substantially modified clinical management disease offering anti-H. therapy definitive cure for great majority patients suffering from ulcers. new classification attains clear distinction H. pylori-positive or other less frequent etiologies (Tab. 1), thereby addressing proper each entity. Management consists antibiotics addition acid-suppressive agents.