AGGRESSIVE GRANULAR CELL AMELOBLASTOMA

摘要: Granular cell ameloblastoma (GCA) is a rare histologic variant of characterized by the presence granular cells, which have abundant cytoplasm filled with eosinophilic granules that resemble lysosomes. A 37-year-old male patient was referred to maxillofacial surgery clinic swelling in mandible noticed 10 years earlier. Two previous biopsy results were suggestive ameloblastoma. Intraorally, there nodular right alveolar ridge involving region premolars and molars, computed tomography showed an expansible multilocular lytic lesion. Histologic examination revealed lesion composed fibrous stroma sheets presenting extensive transformation, surrounded peripheral ameloblast-like cells. Immunohistochemistry negativity for Ki-67. The diagnosis GCA. marginal resection performed, microscopic confirmed diagnosis. remains monitoring, reconstruction will be held soon.