EEG correlates of mescaline-induced pathological aggression in rats

摘要: Electroencephalographic changes in limbic and cortical structures freely moving male rats were examined before after the delivery of footshock, presentation a sedated opponent, administration mescaline hydrochloride (50mg/kg ip). These stimuli presented separately did not produce significantly abnormal EEG activity. However, all three together produced epileptiform spike wave activity basolateral amygdala subjects. This was associated with biting who generally remained passive never attempted aggressive retaliation. Epileptiform seen ventral hippocampus or cerebral cortex. results suggest an association between mescaline-induced pathological aggression electrical amygdala. A possible mechanism for this is discussed.