Sequence analysis of the human thymidine kinase gene promoter: comparison with the human PCNA promoter.
作者： Gordon J. Sauvé , Kenneth E. Lipson , Sing-Tsunc Chen , Renato Baserga
DOI: 10.3109/10425179009041343
关键词:
摘要: We report the sequence of 4264 nucleotides 5′ flanking human thymidine kinase gene, a gene that is maximally expressed at G1/S boundary cell cycle. The position nucleotide sequences which can act as binding sites for trans-acting factors, Sp-1, AP-1/jun, AP-2, OTF-1 and CAAT box factors well other potential cis-acting have been mapped. organization these in promoter PCNA (another boundary) are shown comparison. role may play transcriptional regulation genes discussed.
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