Effect of unilateral and bilateral castration and cryptorchidism on serum gonadotrophins in the rat.

摘要: Abstract The effects of unilateral and bilateral cryptorchidism castration on serum concentrations testosterone, FSH LH in adult male rats were examined. results provide no evidence for compensatory growth or development the remaining scrotal testes up to 32 days after castration, although testis unilaterally cryptorchid showed enlargement when compared with those control (P less than 0 - 05) at days. Unilateral treatments had few significant hormones, but testosterone was increased day 4 castrated rats, controls, levels higher 16 05). Bilateral caused an increase within by 8 0-05) surgery, both hormones reaching double found 01) 16, while maintained above values. resulted a marked decrease sharp gonadotrophins. nearly doubled fourfold their 773% (LH) 287% (FSH) values 01). observations support hypothesis separate, testosterone-independent feedback system hypophysis.