作者: S. Esposito , C. Tagliabue , S. Bosis , V. Ierardi , M. Gambino
关键词:
摘要: Despite the potential for protection against a broad spectrum of pathogens, availability an increased number effective vaccines could lead to significant reduction in vaccination coverage as result issues with implementation new within existing protocols. To overcome these problems, development combined has been promoted. The use offers benefits, including patient visits, reduced complications associated multiple intramuscular injections, decreased costs stocking and administering separate vaccines, lowering risk delayed or missed vaccinations. hexavalent vaccine includes antigens diphtheria, tetanus, acellular pertussis (DTaP), hepatitis B (HBsAg), poliomyelitis (P1, P2, P3) Haemophilus influenzae type (Hib) infections. primary goal this review is discuss immunogenicity, efficacy, safety tolerability several preparations that are either commercially available still under development.