Does antibiotic lock therapy prevent catheter-associated bacteremia in hemodialysis?

摘要: Central venous catheter-related blood stream infection is a major cause of morbidity and mortality in patients with renal disease treated hemodialysis. Antibiotic lock solutions can be effective preventing this complication Searching Epistemonikos database, which maintained by screening more than twenty databases, we identified eight systematic reviews including seventeen randomized trials. We combined the evidence using meta-analysis generated summary findings table following GRADE approach. concluded that antibiotic probably decrease hemodialysis patients.