Cannabinoids Therapeutic Use: What Is Our Current Understanding Following the Introduction of THC, THC:CBD Oromucosal Spray and Others?

摘要: The complexity of the endocannabinoid (eCB) system is becoming better understood and new drivers eCB signaling are emerging. Modulation activities can be therapeutic in a number diseases. Research into has been paralleled by development agents that interact with cannabinoid receptors. In this regard it should remembered herbal cannabis contains myriad active ingredients, individual cannabinoids have quite distinct biological requiring independent studies. Areas covered: This article reviews most important current data involving relation to human diseases, reflect present (based mainly on used prescription medicine, THC/CBD oromucosal spray) potential future uses cannabinoid-based therapy. Expert commentary: From different possibilities, spray clinical use for approximately five years numerous countries world-wide management multiple sclerosis (MS)-related moderate severe resistant spasticity. Clinical trials confirmed its efficacy tolerability. Other diseases which currently being investigated include various pain states, Alzheimer's disease, Parkinson's Huntington's disease epilepsy. continued characterization remains important.