Nitric oxide: a pathogenetic factor in autoimmunity
作者： Hubert Kolb , Victoria Kolb-Bachofen
DOI: 10.1016/0167-5699(92)90118-Q
关键词:
摘要: Nitric oxide (NO) has been identified recently as a multifunctional mediator, produced by, and acting on, most cells of the body. Besides its function endothelium-derived relaxing factor, neurotransmitter an immune defence molecule, evidence is accumulating that NO participates in inflammatory- autoimmune-mediated tissue destruction. Modulation synthesis action represents new approach to treatment inflammatory autoimmune conditions.
elsevier.com
sci-hub.se 参考文章(25)
G Kantwerk-Funke, H Kolb, V Burkart, V Kolb-Bachofen, B Appels, J Funda, Spontaneous cytotoxicity of macrophages against pancreatic islet cells. Journal of Immunology. ,vol. 142, pp. 3803- 3808 ,(1989)
Garth L. Nicolson, Isaiah J. Fidler, Limin Li, Direct in vitro lysis of metastatic tumor cells by cytokine-activated murine vascular endothelial cells. Cancer Research. ,vol. 51, pp. 245- 254 ,(1991)
C D Mills, Molecular basis of suppressor macrophages : arginine metabolism via the nitric oxide synthetase pathway Journal of Immunology. ,vol. 146, pp. 2719- 2723 ,(1991)
J M Langrehr, R D Curran, R L Simmons, T R Billiar, R A Hoffman, Alloantigen-induced activation of rat splenocytes is regulated by the oxidative metabolism of L-arginine Journal of Immunology. ,vol. 145, pp. 2220- 2226 ,(1990)
R M Palmer, S Moncada, E A Higgs, NITRIC OXIDE: PHYSIOLOGY, PATHOPHYSIOLOGY, AND PHARMACOLOGY Pharmacological Reviews. ,vol. 43, pp. 109- 142 ,(1991)
JEAN-CLAUDE Drapier, JOHN B Hibbs Jr, Differentiation of murine macrophages to express nonspecific cytotoxicity for tumor cells results in L-arginine-dependent inhibition of mitochondrial iron-sulfur enzymes in the macrophage effector cells. Journal of Immunology. ,vol. 140, pp. 2829- 2838 ,(1988)
N. Welsh, K. Bendtzen, S. Sandler, Influence of Protease on Inhibitory and Stimulatory Effects of Interleukin 1β on β-Cell Function Diabetes. ,vol. 40, pp. 290- 294 ,(1991) , 10.2337/DIAB.40.2.290
C. Southern, D. Schulster, I.C. Green, Inhibition of insulin secretion by interleukin-1β and tumour necrosis factor-α via an L-arginine-dependent nitric oxide generating mechanism FEBS Letters. ,vol. 276, pp. 42- 44 ,(1990) , 10.1016/0014-5793(90)80502-A
M. Di Rosa, M. Radomski, R. Carnuccio, S. Moncada, Glucocorticoids inhibit the induction of nitric oxide synthase in macrophages. Biochemical and Biophysical Research Communications. ,vol. 172, pp. 1246- 1252 ,(1990) , 10.1016/0006-291X(90)91583-E
K.G.M. Park, P.D. Hayes, O. Eremin, H. Sewell, K.G.M. Park, P.J. Garlick, Stimulation of lymphocyte natural cytotoxicity by L-arginine The Lancet. ,vol. 337, pp. 645- 646 ,(1991) , 10.1016/0140-6736(91)92456-C