Rapid and simple cannulation technique for repeated sampling of cerebrospinal fluid in the conscious rabbit.

摘要: A cannulation technique for continuous sampling of cerebrospinal fluid in unanesthetized freely moving rabbits was established. permanent Teflon catheter constructed easily and inexpensively from commercially available material placed into the cisterna magna fixed to skull by anchoring screws dental cement. The surgical procedure required a minimum time induced minimal trauma, allowing studies which physiologic conditions are required. foreign body reaction, system had dead volume, its size small enough allow simultaneous implantation other devices.