Seed Dormancy in Arabidopsis Is Controlled by Alternative Polyadenylation of DOG1
作者： Malgorzata Cyrek , Halina Fedak , Arkadiusz Ciesielski , Yanwu Guo , Aleksandra Sliwa
DOI: 10.1104/PP.15.01483
关键词:
摘要: DOG1 (Delay of Germination 1) is a key regulator seed dormancy in Arabidopsis (Arabidopsis thaliana) and other plants. Interestingly, the C terminus either absent or not conserved many plant species. Here, we show that Arabidopsis, transcript subject to alternative polyadenylation. In line with this, mutants RNA 3' processing complex display weakened parallel defects proximal polyadenylation site selection, suggesting short functional. This corroborated by finding proximally polyadenylated mRNA translated vivo complements dog1 mutant. summary, our findings indicate protein isoform produced from player establishment characterizes set required for production functional transcript.
plantphysiol.org
oup.com参考文章(50)
Jacek Krol, Ilona Krol, Claudia Patricia Patino Alvarez, Michele Fiscella, Andreas Hierlemann, Botond Roska, Witold Filipowicz, A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture Nature Communications. ,vol. 6, pp. 7305- 7305 ,(2015) , 10.1038/NCOMMS8305
Christine Mayr, David P. Bartel, Widespread Shortening of 3 0 UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells PMC. ,(2009)
Xiaohui Wu, Yong Zeng, Jinting Guan, Guoli Ji, Rongting Huang, Qingshun Q. Li, Genome-wide characterization of intergenic polyadenylation sites redefines gene spaces in Arabidopsis thaliana BMC Genomics. ,vol. 16, pp. 511- 511 ,(2015) , 10.1186/S12864-015-1691-1
Andreas R. Gruber, Georges Martin, Walter Keller, Mihaela Zavolan, Means to an end: mechanisms of alternative polyadenylation of messenger RNA precursors Wiley Interdisciplinary Reviews - Rna. ,vol. 5, pp. 183- 196 ,(2014) , 10.1002/WRNA.1206
KAI GRAEBER, KAZUMI NAKABAYASHI, EMMA MIATTON, GERHARD LEUBNER-METZGER, WIM J. J. SOPPE, Molecular mechanisms of seed dormancy Plant Cell and Environment. ,vol. 35, pp. 1769- 1786 ,(2012) , 10.1111/J.1365-3040.2012.02542.X
Hiroyuki Nonogaki, Seed dormancy and germination-emerging mechanisms and new hypotheses. Frontiers in Plant Science. ,vol. 5, pp. 233- 233 ,(2014) , 10.3389/FPLS.2014.00233
Alexander Sherstnev, Céline Duc, Christian Cole, Vasiliki Zacharaki, Csaba Hornyik, Fatih Ozsolak, Patrice M Milos, Geoffrey J Barton, Gordon G Simpson, Direct Sequencing of Arabidopsis thaliana RNA Reveals Patterns of Cleavage and Polyadenylation Nature Structural & Molecular Biology. ,vol. 19, pp. 845- 852 ,(2012) , 10.1038/NSMB.2345
Ran Elkon, Alejandro P. Ugalde, Reuven Agami, Alternative cleavage and polyadenylation: extent, regulation and function Nature Reviews Genetics. ,vol. 14, pp. 496- 506 ,(2013) , 10.1038/NRG3482
Magid Shirzadegan, Peter Christie, Jeffrey R. Seemann, An efficient method for isolation of RNA from tissue cultured plant cells Nucleic Acids Research. ,vol. 19, pp. 6055- 6055 ,(1991) , 10.1093/NAR/19.21.6055
M. Teresa Melillo, Paola Leonetti, Michel Bongiovanni, Philippe Castagnone-Sereno, Teresa Bleve-Zacheo, Modulation of reactive oxygen species activities and H2O2 accumulation during compatible and incompatible tomato–root‐knot nematode interactions New Phytologist. ,vol. 170, pp. 501- 512 ,(2006) , 10.1111/J.1469-8137.2006.01724.X