Clinical application of immune-enhanced enteral nutrition in patients with advanced gastric cancer after total gastrectomy
作者： Hua LIU , Wei LING , Zhi Yong SHEN , Xin JIN , Hui CAO
DOI: 10.1111/J.1751-2980.2012.00596.X
关键词:
摘要: OBJECTIVE: To determine whether immune-enhanced enteral nutrition (EN) was effective on nutritional status, immune function, surgical outcomes and days of hospitalization after total gastrectomy for patients with advanced gastric cancer (AGC). METHODS: From August 2005 to May 2011, 78 AGC who underwent a were enrolled divided randomly into three groups: EN (EN + glutamine [Gln]) group, standard group control group. Serum parameters including protein, albumin, proalbumin transferrin examined preoperative day 1, postoperative 2 12. Levels immunoglobulin M (IgM), G (IgG), natural killer (NK) cells, CD4+ CD8+ T cells also compared. RESULTS: The formulas tolerated well in all the except 5 mild complications. + Gln groups showed faster onset flatus shorter duration than On 12, serum levels Gln significantly higher those (P < 0.05). NK IgM IgG increased prominently, before operation as groups. CONCLUSION: Immune-enhanced can improve status function gastrectomy.
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