作者: Miodrag Gužvić , Christoph A. Klein
DOI: 10.1007/978-3-540-74386-6_6
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摘要: This chapter summarizes current concepts of dissemination (the processes leaving the primary lesion and homing to surviving in a new environment) metastasis successful growth cancer cell clinically detectable, distant colony) role microenvironmental as well systemically acting factors these processes. We review recent research on genotypes phenotypes early disseminated cells discuss tumour dormancy, angiogenesis, genetic background, aging immune system metastasis.