Environmentally induced nephrotoxicity and histopathological alternations in Wallago attu and Cirrhinus mrigla.

摘要: Fish kidneys are sensitive to chemical changes in the freshwater ecosystem because they directly and constantly exposed chemicals dissolved water. This study evaluated nephrotoxicity Wallago attu Cirrhinus mrigala harvested from Chenab River an area of industrial sewage waste disposal. Induced histological alternation data were correlated severity environmental degradation order determine whether this biological system can be used as a tool for monitoring programs. Kidneys two fish species occupying different niches collected stored 24 h 10% formalin. Control upstream polluted river area. Specimens processed using topical methods. The major alterations observed both renal tubule myxospora, hyperemia, glomerulonephritis, degeneration cells, dilation glomerular capillaries, presence pycnotic nuclei hematopoietic tissue, epithelial hypertrophy, vacuolization, reduced lumen tubules, shrinkage glomeruli. Renal tubular atrophy, due extensive degranulation, necrosis glomeruli, expansion, absence Bowman's space, hypertrophied nucleus, hyalinization interstitium, clogging regeneration tubules was also observed. exhibited maximum incidence moderate severe defined having highest "histopathologic alteration index". These found related degradation, indicating stressors freshwater. groups showed normal tissue morphology kidneys.