Hybrid systems for oral delivery of a therapeutic neuropeptide
作者： Natalia N. Sudareva , Olga M. Suvorova , Irina I. Tarasenko , Natalia N. Saprykina , Natalia V. Smirnova
DOI: 10.1016/J.MENCOM.2020.01.008
关键词:
摘要: Several hybrid systems for oral delivery of a therapeutic peptide have been prepared and investigated. Poly(l-glutamic acidco-d-phenylalanine) silica sub-microparticles, porous CaCO3 microparticles Lycopodium clavatum spore capsules were employed as the first level carriers included in sodium alginate granules second carriers. Efficiency encapsulation release rate strongly depended on nature structure
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