Factors That Affect Quality of Life among People Living with HIV Attending an Urban Clinic in Uganda: A Cohort Study.

作者: Doris Mutabazi-Mwesigire , Achilles Katamba , Faith Martin , Janet Seeley , Albert W. Wu

DOI: 10.1371/JOURNAL.PONE.0126810

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摘要: Introduction With the availability of antiretroviral therapy (ART) and primary general care for people living with HIV (PLHIV) in resource limited settings, PLHIV are longer, has been transformed into a chronic illness. People diagnosed started on treatment when they relatively well. Although ART results clinical improvement, ultimate goal is full physical functioning well-being, focus quality life rather than outcomes. However, there little research relationship specific factors to PLHIV. The objective this study was investigate associated among Uganda receiving basic those ART. Methods We enrolled 1274 patients attending an outpatient clinic prospective cohort study. Of these, 640 received All were followed up at 3 6 months. Health related assessed MOS-HIV Survey Global Person Generated Index (GPGI). Multivariate linear regression logistic generalized estimating equations used examine social behavioral disease Physical Summary (PHS) score, Mental (MHS) GPGI. Results Among care, PHS with: sex (p=0.045) - females had lower PHS; age years enrollment (p=0.0001) older depression (p<0.001) depressed PHS. MHS only opportunistic infection (p=0.01) presence MHS. For GPG variables (p=0.03) GPGI; education – higher GPGI (p<0.001). ART, visit (p=0.01), increase time better PHS, also improved level (p=0.002). Patients WHO stage 3&4 compared 1&2 (p=0.006), from baseline six month (p<0.001), males (p=0.01). income (p=0.04), alcohol use (p=0.004), Conclusion Quality over Regardless status, or low female gender risk having poor life. Clinicians policy makers should be aware these findings, address them improve

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