Hormonal Therapy for Prostate Cancer

摘要: Updates on hormonal therapy in the treatment of prostate cancer are presented. The most common is to reduce testosterone castrate levels. A dosage 1 mg diethylstilbestrol daily prolonged survival patients with advanced cancer. leuteinizing hormone-releasing hormone agonists have essentially replaced surgical orchiectomy vast majority clinical settings; however, a major problem hormone- releasing has been surge and flare If initiated early, risk complications significantly decreased. Combined androgen blockade better than monotherapy, although there only small benefit. When deprivation used for short time normal milieu re-established, side effects toxicity include hot flushes, reduction bone mineral density, osteoporosis, anemia. Intermittent might same benefits total suppression fewer effects, increased duration dependence, less cost. 10 steps take when advising about initiation reviewed.