作者: RA Seymour , M Weldon , P Kelly , E Nicholson , JE Hawkesford
DOI: 10.1111/J.1365-2125.1992.TB04057.X
关键词:
摘要: 1. Single doses (500 and 1000 mg) of both buffered aspirin tablets were compared with placebo in a randomised double-blind trial parallel design patients postoperative pain after third molar surgery. 2. Only 500 mg provided significant relief (P = 0.016) during the 5 h investigation period. 3. A correlation 0.004) was observed between overall scores various treatments esterase activity. 4. Buffered preparations afforded slight advantage over control However, duration analgesia short (approximately 2 h). 5. Aspirin activity appears to be an important determinant drug's efficacy dental pain.