Effects of age on cerebrospinal fluid oxytocin levels in free-ranging adult female and infant rhesus macaques.

摘要: There is growing interest in examining oxytocin and social functioning human non-human primates. Studies of biology are typically restricted to peripheral assessments because opportunities collect cerebrospinal fluid (CSF) rare. Several studies have examined CSF levels captive adult primates, but none our knowledge been conducted under free-ranging conditions inclusive infants. The main goal this study was establish feasibility quantifying female infant rhesus monkeys living on Cayo Santiago, PR. were relation individuals’ demographic reproductive characteristics as well plasma cortisol levels. concentrations ranged from 36.02 134.41 pg/ml females (ages 7–26 years; N 31) 35.94 77.3 infants 38–134 days; 17). positively correlated with age negatively age. former correlation driven by status. unrelated dominance rank or In contrast a previous population, did not differ significantly between lactating non-lactating females. These findings: 1) provide data for primates 2) indicate that may be biomarker age-related central nervous system changes across lifespan development. Research now required examine the context monkeys.