Synthesis of high-quality monolayer tungsten disulfide with chlorophylls and its application for enhancing bone regeneration

作者: Yi-Wen Chen , Ming-You Shie , Chien-Hsuan Hsiao , Yu-Chun Liang , Ben Wang

DOI: 10.1038/S41699-020-00168-Y

关键词:

摘要: Due to the population explosion of 21st century, nearly one billion people are over 64 years age and bone fracture is most frequent problems facing both sexes because osteoporosis. However, difficulty in enhancing regeneration repair poses challenges thus, a two-dimensional monolayer material (i.e. tungsten disulfide (WS2)) could be candidates offering possible solution problem. Here, we prepare high-quality WS2 thin sheets large quantity with assistance extracted chlorophyll molecules, natural pigment used photosynthesis, via liquid-phase exfoliation method. Then, exfoliated were mixed polycaprolactone (PCL)/calcium silicate (CS) form biocompatible WS2-based composite. The vivo experiments show that composite was 120% superior commercially available mineral trioxide aggregate (MTA) cement. Moreover, mechanical properties exhibited ~300% enhancement PCL/CS, which commonly materials. Our findings highlight prospects for towards improvement applications.

参考文章(67)
A. Molina-Sánchez, L. Wirtz, Phonons in single-layer and few-layer MoS 2 and WS 2 Physical Review B. ,vol. 84, pp. 155413- ,(2011) , 10.1103/PHYSREVB.84.155413
Andy Nieto, Rupak Dua, Cheng Zhang, Benjamin Boesl, Sharan Ramaswamy, Arvind Agarwal, Three Dimensional Graphene Foam/Polymer Hybrid as a High Strength Biocompatible Scaffold Advanced Functional Materials. ,vol. 25, pp. 3916- 3924 ,(2015) , 10.1002/ADFM.201500876
Joel E. Cohen, Population and climate change. Proceedings of the American Philosophical Society: Held at Philadelphia for Promoting Useful Knowledge. ,vol. 154, pp. 158- 182 ,(2010)
Tofik Ahmed Shifa, Fengmei Wang, Zhongzhou Cheng, Xueying Zhan, Zhenxing Wang, Kaili Liu, Muhammad Safdar, Lianfeng Sun, Jun He, None, A vertical-oriented WS2nanosheet sensitized by graphene: an advanced electrocatalyst for hydrogen evolution reaction Nanoscale. ,vol. 7, pp. 14760- 14765 ,(2015) , 10.1039/C5NR03704B
Saïd Barazzouk, Laurent Bekalé, Surat Hotchandani, Enhanced photostability of chlorophyll-a using gold nanoparticles as an efficient photoprotector Journal of Materials Chemistry. ,vol. 22, pp. 25316- 25324 ,(2012) , 10.1039/C2JM33681B
J. N. Coleman, M. Lotya, A. O'Neill, S. D. Bergin, P. J. King, U. Khan, K. Young, A. Gaucher, S. De, R. J. Smith, I. V. Shvets, S. K. Arora, G. Stanton, H.-Y. Kim, K. Lee, G. T. Kim, G. S. Duesberg, T. Hallam, J. J. Boland, J. J. Wang, J. F. Donegan, J. C. Grunlan, G. Moriarty, A. Shmeliov, R. J. Nicholls, J. M. Perkins, E. M. Grieveson, K. Theuwissen, D. W. McComb, P. D. Nellist, V. Nicolosi, Two-Dimensional Nanosheets Produced by Liquid Exfoliation of Layered Materials Science. ,vol. 331, pp. 568- 571 ,(2011) , 10.1126/SCIENCE.1194975
Gaurav Lalwani, Allan M. Henslee, Behzad Farshid, Priyanka Parmar, Liangjun Lin, Yi-Xian Qin, F. Kurtis Kasper, Antonios G. Mikos, Balaji Sitharaman, Tungsten Disulfide Nanotubes Reinforced Biodegradable Polymers for Bone Tissue Engineering Acta Biomaterialia. ,vol. 9, pp. 8365- 8373 ,(2013) , 10.1016/J.ACTBIO.2013.05.018
Tanyuan Wang, Lu Liu, Zhiwei Zhu, Pagona Papakonstantinou, Jingbo Hu, Hongyun Liu, Meixian Li, Enhanced electrocatalytic activity for hydrogen evolution reaction from self-assembled monodispersed molybdenum sulfide nanoparticles on an Au electrode Energy and Environmental Science. ,vol. 6, pp. 625- 633 ,(2013) , 10.1039/C2EE23513G
Bin Yu, Xin Wang, Xiaodong Qian, Weiyi Xing, Hongyu Yang, Liyan Ma, Ying Lin, Saihua Jiang, Lei Song, Yuan Hu, Siuming Lo, Functionalized graphene oxide/phosphoramide oligomer hybrids flame retardant prepared via in situ polymerization for improving the fire safety of polypropylene RSC Advances. ,vol. 4, pp. 31782- 31794 ,(2014) , 10.1039/C3RA45945D