Effects of short-term moderate alcohol administration on oxidative stress and nutritional status in healthy males.

作者: Giovanni Addolorato , Lorenzo Leggio , Veronica Ojetti , Esmeralda Capristo , Giovanni Gasbarrini

DOI: 10.1016/J.APPET.2007.05.008

关键词:

摘要: Abstract The effects of moderate amounts different alcoholic beverages on oxidative stress and nutritional parameters were investigated in 40 healthy subjects. Ethanol 40 g/day was administered at the two main meals for 30 days by beer (group A), wine B) or spirit C); controls D) maintaned abstinence. Malondyaldeide (MDA), adenosine-triphosphate (ATP), reduced-glutathione (GSH), E-vitamin status evaluated start (T0) end (T1) study. At T1 did not present significant changes assessed parameters, while a increase malondyaldeide (MDA) decrease group A, B C ATP observed. Fat mass (FM) increased slightly A decreased C. antioxidant lipoperoxidation parameters. However some these appeared attenuated when ethanol consumed wine. Finally, short-term intake to influence FM, although it able significantly affect body composition.

参考文章(58)
Antonio Gasbarrini, Giovanni Addolorato, Mara Simoncini, Giovanni Gasbarrini, Paolo Fantozzi, Francesca Mancini, Luigi Montanari, Mirella Nardini, Andrea Ghiselli, Cristina Scaccini, Beer affects oxidative stress due to ethanol in rats. Digestive Diseases and Sciences. ,vol. 43, pp. 1332- 1338 ,(1998) , 10.1023/A:1018832513539
Diane L. Lucas, Ricardo A. Brown, Momtaz Wassef, Thomas D. Giles, Alcohol and the Cardiovascular System: Research Challenges and Opportunities Journal of the American College of Cardiology. ,vol. 45, pp. 1916- 1924 ,(2005) , 10.1016/J.JACC.2005.02.075
Christo D Venkov, Paul R Myers, Miles A Tanner, Ming Su, Douglas E Vaughan, None, Ethanol increases endothelial nitric oxide production through modulation of nitric oxide synthase expression. Thrombosis and Haemostasis. ,vol. 81, pp. 638- 642 ,(1999) , 10.1055/S-0037-1614538
Antonio Gasbarrini, Giovanni Addolorato, Cristiana Di Campli, Mara Simoncini, Salvatore Montemagno, Marco Castagneto, Cristiano Padalino, Paolo Pola, Giovanni Gasbarrini, Gender affects reperfusion injury in rat liver Digestive Diseases and Sciences. ,vol. 46, pp. 1305- 1312 ,(2001) , 10.1023/A:1010679716435
John A. Buege, Steven D. Aust, Microsomal lipid peroxidation. Methods in Enzymology. ,vol. 52, pp. 302- 310 ,(1978) , 10.1016/S0076-6879(78)52032-6
J G Bieri, T J Tolliver, G L Catignani, Simultaneous determination of alpha-tocopherol and retinol in plasma or red cells by high pressure liquid chromatography. The American Journal of Clinical Nutrition. ,vol. 32, pp. 2143- 2149 ,(1979) , 10.1093/AJCN/32.10.2143
Mirella Nardini, Massimo D'Aquino, Gianni Tomassi, Vincenzo Gentili, Maurizio Di Felice, Cristina Scaccini, Inhibition of human low-density lipoprotein oxidation by caffeic acid and other hydroxycinnamic acid derivatives Free Radical Biology and Medicine. ,vol. 19, pp. 541- 552 ,(1995) , 10.1016/0891-5849(95)00052-Y
Richard J. Hendrickson, S.Steve Okada, Paul A. Cahill, Ekua Yankah, James V. Sitzmann, Eileen M. Redmond, Ethanol Inhibits Basal and Flow-Induced Vascular Smooth Muscle Cell Migrationin Vitro Journal of Surgical Research. ,vol. 84, pp. 64- 70 ,(1999) , 10.1006/JSRE.1999.5605
T. Sepp�l�, C. Str�mberg, I. Bergman, Effects of zimeldine, mianserin and amitriptyline on psychomotor skills and their interaction with ethanol a placebo controlled cross-over study. European Journal of Clinical Pharmacology. ,vol. 27, pp. 181- 189 ,(1984) , 10.1007/BF00544043
Elliot Rapaport, Thrombolytic Agents in Acute Myocardial Infarction New England Journal of Medicine. ,vol. 320, pp. 861- 864 ,(1989) , 10.1056/NEJM198903303201309