Parathyroid Hormone as a Trophic Hormone for 1,25-Dihydroxyvitamin D3, the Metabolically Active Form of Vitamin D

作者: H. F. DeLuca

DOI: 10.1056/NEJM197208032870511

关键词:

摘要: Well known to the clinician is fact that hypoparathyroid patients require large amounts of vitamin D or its close analogue, dihydrotachysterol, for maintenance reasonable plasma calcium concentrations. Not so well recognized presence metabolites required parathyroid hormone carry out bone mobilization function in elevation serum concentration.1 Finally, who are resistant massive have been described.2 From these facts it seems clear both and . . .

参考文章(2)
I. T. Boyle, R. W. Gray, H. F. Deluca, Regulation by Calcium of In Vivo Synthesis of 1,25-Dihydroxycholecalciferol and 21,25-Dihydroxycholecalciferol Proceedings of the National Academy of Sciences of the United States of America. ,vol. 68, pp. 2131- 2134 ,(1971) , 10.1073/PNAS.68.9.2131
C. Y. Pak, Treatment of vitamin D-resistant hypoparathyroidism with 25-hydroxycholecalciferol Archives of Internal Medicine. ,vol. 126, pp. 239- 247 ,(1970) , 10.1001/ARCHINTE.126.2.239