Molecular Physiology of Mammalian K(+)-Cl- Cotransporters
作者： Adriana Mercado , Gerardo Gamba , David B. Mount
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摘要: Potassium-chloride (K-Cl) cotransport is a major pathway for the coupled, electroneutral exit of K and Cl from perhaps all mammalian cells. This transport activity mediated by KCC proteins encoded four genes in SLC12 family cation-chloride cotransporters. Almost quarter century has passed since initial papers describing K-Cl cotransport; 3 symposium honoring one most prolific investigators field seems fitting opportunity to review progress molecular physiology these important transporters. serves as an update prior comprehensive reviews on general its role specific tissues. 6
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