Method of anoxia treatment using prostaglandin analogues

摘要: The invention provides a new method for the treatment of anoxia brain cells using PGI1 derivative formula: ##STR1## wherein R1 represents hydrogen or lower alkyl and R2 2-methylhexyl, 3-propylcyclopentyl, 3-butylcyclopentyl 4-propylcyclohexyl, PGI2 ##STR2## R3 R4 cyclopentyl, cyclohexyl, ##STR3## R5 R6 pentyl, 1-methylpentyl, 1-methyl-5-chloropentyl, 2-methyl-5-chloropentyl, 3-ethylcyclopentyl, 3-butylcyclopentyl, 3-(2-chloroethyl)cyclopentyl, 4-ethylcyclohexy, cyclohexylmethyl PGE1 ##STR4## X methylene carbonyl (i) when methylene, Y ethylene trans-vinylene, R7 carboxy alkoxycarbonyl R8 2-methylhexyl 1-cyclohexylethyl (ii) carbonyl, ethylene, carboxyl, alkoxycarbonyl, glycoloyl hydroxymethyl cyclodextrin clathrate non-toxic salt thereof.