Cadmium concentration in biological media of breast cancer patients

作者: Loreta Strumylaite , Algirdas Bogusevicius , Olegas Abdrachmanovas , Dale Baranauskiene , Rima Kregzdyte

DOI: 10.1007/S10549-010-1007-8

关键词:

摘要: The study aimed to determine and compare cadmium (Cd) concentration in different biological media of breast cancer benign tumor patients. Concentration Cd was determined tissue, urine, blood 57 51 Two samples tissue from each patient, i.e., healthy were taken for the analysis. by atomic absorption spectrometry (Perkin-Elmer, Zeeman 3030). mean patients 0.053 μg/g (95% confidence intervals, CI 0.042-0.065) sample 0.02 0.014-0.026) (P 0.05). content malignant significantly differed that < 0.01). Cancer with positive estrogen receptors (ERs) had greater compared negative ERs = 0.035). Adjusted creatinine, urine higher than controls 0.001). In patients, a Spearman's correlation found between (r 0.44 r 0.39, respectively, P Correlation number cigarettes smoked during lifetime suggestive 0.59, 0.075). data obtained show support possible relationship cancer.

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