Heat Shock Transcription Factor Hsf1 Is Involved in Tumor Progression via Regulation of Hypoxia-Inducible Factor 1 and RNA-Binding Protein HuR

作者: V. L. Gabai , L. Meng , G. Kim , T. A. Mills , I. J. Benjamin

DOI: 10.1128/MCB.05921-11

关键词:

摘要: … but instead causes senescence which is accompanied by accumulation of a cell cycle inhibitor, p21, and decrease in levels of the cell cycle promoter and apoptosis inhibitor survivin (28…

参考文章(38)
Isabel López de Silanes, Ashish Lal, Myriam Gorospe, HuR: post-transcriptional paths to malignancy. RNA Biology. ,vol. 2, pp. 11- 13 ,(2005) , 10.4161/RNA.2.1.1552
Nava Zaarur, Vladimir L. Gabai, John A. Porco, Stuart Calderwood, Michael Y. Sherman, Targeting Heat Shock Response to Sensitize Cancer Cells to Proteasome and Hsp90 Inhibitors Cancer Research. ,vol. 66, pp. 1783- 1791 ,(2006) , 10.1158/0008-5472.CAN-05-3692
C. T. Guy, M. A. Webster, M. Schaller, T. J. Parsons, R. D. Cardiff, W. J. Muller, Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease Proceedings of the National Academy of Sciences of the United States of America. ,vol. 89, pp. 10578- 10582 ,(1992) , 10.1073/PNAS.89.22.10578
R Kulshreshtha, R V Davuluri, G A Calin, M Ivan, A microRNA component of the hypoxic response Cell Death & Differentiation. ,vol. 15, pp. 667- 671 ,(2008) , 10.1038/SJ.CDD.4402310
Isabel López de Silanes, Jinshui Fan, Xiaoling Yang, Alan B Zonderman, Olga Potapova, Ellen S Pizer, Myriam Gorospe, Role of the RNA-binding protein HuR in colon carcinogenesis. Oncogene. ,vol. 22, pp. 7146- 7154 ,(2003) , 10.1038/SJ.ONC.1206862
Carlo M. Croce, Causes and consequences of microRNA dysregulation in cancer Nature Reviews Genetics. ,vol. 10, pp. 704- 714 ,(2009) , 10.1038/NRG2634
Kotb Abdelmohsen, Ashish Lal, Hyeon Ho Kim, Myriam Gorospe, Posttranscriptional orchestration of an anti-apoptotic program by HuR. Cell Cycle. ,vol. 6, pp. 1288- 1292 ,(2007) , 10.4161/CC.6.11.4299
Bradley M. Lunde, Claire Moore, Gabriele Varani, RNA-binding proteins: modular design for efficient function Nature Reviews Molecular Cell Biology. ,vol. 8, pp. 479- 490 ,(2007) , 10.1038/NRM2178
Lila Pirkkala, Päivi Nykänen, LEA Sistonen, None, Roles of the heat shock transcription factors in regulation of the heat shock response and beyond The FASEB Journal. ,vol. 15, pp. 1118- 1131 ,(2001) , 10.1096/FJ00-0294REV
Scott W. Lowe, Enrique Cepero, Gerard Evan, Intrinsic tumour suppression Nature. ,vol. 432, pp. 307- 315 ,(2004) , 10.1038/NATURE03098