Selective venous sampling catheterisation for localisation of persisting medullary thyroid carcinoma

摘要: Selective venous sampling catheterisation was performed in 19 patients with medullary thyroid carcinoma without known distant metastases for persistent hypercalcitoninaemia after surgery. Calcitonin (CT) gradients were found the neck and/or mediastinum 18 and five at sites also. After catheterisation, 13 subjected to repeat Neck mediastinal tumour foci 12 of CT gradients. Of these, nine had only cervicomediastinal gradients: reoperation, serum level normalised one, significantly decreased five, did not change three, no relapse occurred a mean follow-up 5.3 years. Distant emerged clinically all one 14 gradient. In conclusion, selective is most sensitive tool localisation residual disease early detection metastases. However, local disease, biochemical cure rarely obtained reoperation.