Cost-effectiveness of the psycho-educational blended (group and online) intervention HypoAware compared with usual care for people with Type 1 and insulin-treated Type 2 diabetes with problematic hypoglycaemia: analyses of a cluster-randomized controlled

摘要: Aims To evaluate the cost-effectiveness of HypoAware, a blended (group and online) psycho-educational intervention based on evidence-based Blood Glucose Awareness Training, in comparison with usual care people Type 1 2 diabetes high risk severe hypoglycaemia. Methods We performed an economic evaluation, from societal healthcare perspective, that used data 6-month, multicentre, cluster-randomized controlled trial (n = 137). Results The proportion at least one hypoglycaemic event per 6 months was 0.22 lower (95% CI -0.39 to -0.06) impaired hypoglycaemia awareness 0.16 -0.34 0.02) HypoAware group. There no difference quality-adjusted life-years (-0.0; 95% -0.05 0.05). mean total costs group were EUR708 higher than -951 2298). incremental cost prevented EUR2,233. At willingness-to-pay threshold EUR20,000 prevented, probability cost-effective 54% perspective 55% perspective. For ratio EUR119,360/quality-adjusted life-year gained low all ceiling ratios. Conclusions Based present study, we conclude is not compared care. Further research less well-resourced settings more severely affected patients warranted. (Clinical Trials Registry no: Dutch Trial Register NTR4538.).