Mitochondrial numbers increase during glucose deprivation in the slime mold Physarum polycephalum
作者： Christina Oettmeier , Hans-Günther Döbereiner
DOI: 10.1007/S00709-019-01410-1
关键词:
摘要: Glucose deprivation in the slime mold Physarum polycephalum leads to a specific morphotype, highly motile mesoplasmodium. We investigated ultrastructure of both mesoplasmodia and non-starved plasmodia found significantly increased numbers mitochondria glucose-deprived mesoplasmodia. The volume individual was same growth forms. conjecture that number correlates with metabolic state cell: When glucose is absent, forced switch different pathways, which occur inside mitochondria. Furthermore, catabolic cue (such as AMP-activated protein kinase (AMPK)) could stimulate mitochondrial biogenesis.
springer.com
paperity.org参考文章(51)
E. M. Goodman, H. P. Rusch, Glycogen inPhysarum polycephalum Cellular and Molecular Life Sciences. ,vol. 25, pp. 580- 580 ,(1969) , 10.1007/BF01896520
Fernando Bartolomé, Andrey Y. Abramov, Measurement of mitochondrial NADH and FAD autofluorescence in live cells. Methods of Molecular Biology. ,vol. 1264, pp. 263- 270 ,(2015) , 10.1007/978-1-4939-2257-4_23
John W. Daniel, Jacqueline Kelley, Harold P. Rusch, HEMATIN-REQUIRING PLASMODIAL MYXOMYCETE Journal of Bacteriology. ,vol. 84, pp. 1104- 1110 ,(1962) , 10.1128/JB.84.5.1104-1110.1962
Wilhelm Stockem, Klaudia Brix, Analysis of Microfilament Organization and Contractile Activities in Physarum International Review of Cytology-a Survey of Cell Biology. ,vol. 149, pp. 145- 215 ,(1994) , 10.1016/S0074-7696(08)62088-4
Carsten Lundby, Robert A. Jacobs, Adaptations of skeletal muscle mitochondria to exercise training. Experimental Physiology. ,vol. 101, pp. 17- 22 ,(2016) , 10.1113/EP085319
Induction of mitochondrial migration in the slime mold Physarum polycephalum Plant and Cell Physiology. ,vol. 19, pp. 1561- 1564 ,(1978) , 10.1093/OXFORDJOURNALS.PCP.A075742
N.D. Evans, L. Gnudi, O.J. Rolinski, D.J.S. Birch, J.C. Pickup, Glucose-dependent changes in NAD(P)H-related fluorescence lifetime of adipocytes and fibroblasts in vitro: potential for non-invasive glucose sensing in diabetes mellitus. Journal of Photochemistry and Photobiology B-biology. ,vol. 80, pp. 122- 129 ,(2005) , 10.1016/J.JPHOTOBIOL.2005.04.001
Craig Blackstone, Chuang-Rung Chang, Mitochondria unite to survive Nature Cell Biology. ,vol. 13, pp. 521- 522 ,(2011) , 10.1038/NCB0511-521
Robim M. Rodrigues, Peter Macko, Taina Palosaari, Maurice P. Whelan, Autofluorescence microscopy: a non-destructive tool to monitor mitochondrial toxicity. Toxicology Letters. ,vol. 206, pp. 281- 288 ,(2011) , 10.1016/J.TOXLET.2011.06.025
C. Nations, V. F. Allison, H. C. Aldrich, R. G. Allen, Biological oxidation and the mobilization of mitochondrial calcium during the differentiation ofPhysarum polycephalum Journal of Cellular Physiology. ,vol. 140, pp. 311- 316 ,(1989) , 10.1002/JCP.1041400217