12 – Specific Sites of Chromosomal Radiation-induced Rearrangements
作者： L. SABATIER , M. MULERIS , M. PRIEUR , W. AL ACHKAR , F. HOFFSCHIR
DOI: 10.1016/B978-0-12-388176-2.50023-0
关键词:
摘要: Publisher Summary The possibility that chromosomal rearrangements result from preferential breakage at specific sites, called hot-spots, remains disputable. These hot-spots correspond to some fragile and they are involved in acquired pathology. The exact localization of many sites approximate. mapping oncogenes is cases incomplete also have a nonobjective definition described biased analyses small samples. various uncertainties do not exclude the presumed loci these overlap all along chromosome arms, making any formal conclusion quite trivial. To avoid biases analyses, large samples accumulated an appropriate statistical treatment being developed.
sci-hub.st 参考文章(19)
Luc Hens, Hella Baumann, Thomas Cremer, Axel Sutter, Jan J. Cornelis, Christoph Cremer, Immunocytochemical localization of chromatin regions UV-microirradiated in S phase or anaphase Experimental Cell Research. ,vol. 149, pp. 257- 269 ,(1983) , 10.1016/0014-4827(83)90397-X
Bernard Dutrillaux, Evani Viegas-Pequignot, Alain Aurias, Michelle Prod'Homme, Michéle Sportes, Marguerite Prieur, Tentative estimate of the risk of chromosomal disease due to radiation-induced translocations in man. Mutation Research. ,vol. 82, pp. 191- 200 ,(1981) , 10.1016/0027-5107(81)90149-4
Y. Kano, J.B. Little, Site-specific chromosomal rearrangements induced in human diploid cells by x-irradiation. Cytogenetic and Genome Research. ,vol. 41, pp. 22- 29 ,(1986) , 10.1159/000132191
M MULERIS, M PARAVATOUPETSOTA, B DUTRILLAUX, Diagrammatic representation for chromosomal mutagenesis studies: II. Radiation-induced rearrangements in Macaca fascicularis Mutation Research. ,vol. 126, pp. 93- 103 ,(1984) , 10.1016/0027-5107(84)90173-8
B. Dutrillaux, J. Couturier, E. Viegas-P�quignot, G. Schaison, Localization of chromatid breaks in Fanconi's anemia, using three consecutive stains Human Genetics. ,vol. 37, pp. 65- 71 ,(1977) , 10.1007/BF00293773
A. Aurias, M. Prieur, B. Dutrillaux, J. Lejeune, Systematic analysis of 95 reciprocal translocations of autosomes Human Genetics. ,vol. 45, pp. 259- 282 ,(1978) , 10.1007/BF00278725
Claude Dubos, Evani Viegas Pequignot, Bernard Dutrillaux, Localization of γ-rays induced chromatid breaks using a three consecutive staining-technique Mutation Research. ,vol. 49, pp. 127- 131 ,(1978) , 10.1016/0027-5107(78)90084-2
M PARAVATOUPETSOTA, M MULERIS, M PRIEUR, B DUTRILLAUX, Diagrammatic representation for chromosomal mutagenesis studies. III. Radiation-induced rearrangements in Pan troglodytes (chimpanzee). Mutation Research. ,vol. 149, pp. 57- 66 ,(1985) , 10.1016/0027-5107(85)90009-0
B. Dutrillaux, E. Viegas-P�quignot, A. Aurias, M. Mouthuy, M. Prieur, Non random position of metaphasic chromosomes: a study of radiation induced and constitutional chromosome rearrangements. Human Genetics. ,vol. 59, pp. 208- 210 ,(1981) , 10.1007/BF00283665
Frederick Hecht, Grant R. Sutherland, Fragile sites and cancer breakpoints Cancer Genetics and Cytogenetics. ,vol. 12, pp. 179- 181 ,(1984) , 10.1016/0165-4608(84)90132-8