Microstructuring of Surfaces for Bio-Medical Applications

摘要: In recent years microfluidic devices became of great interest, as they offer a wide range bio-analytical and fluid processing applications through the utilization size effects. Especially mass manufacturing disposable polymeric by hot embossing or injection molding is expected to have high economic potential. It known, that channels areas showing localized change in wettability can considerably improve tasks like mixing droplet generation. Chemical approaches, polymerization lauryl acrylate, were successfully shown achieve hydrophobic coatings for micro but are not suitable manufacturing. Since microstructures known provide water repellent properties surfaces, this paper focuses on applicability diamond grooving Diamond Micro Chiseling (DMC) processes manufacture microstructured brass molds inserts, order their replica. Major design features structures, height 6 16μm aspect ratios between 0.5 3.2 derived from natural example lotus leaf. Molding carried out using two component silicone filler. The performance replicated surfaces evaluated contact angle measurements. After presenting methodology results, will conclude how transfer investigated microstructuring methods mold inserts replication chips with channels.