Global patterns of human mitochondrial DNA and Y-chromosome structure are not influenced by higher migration rates of females versus males.

作者: Jason A Wilder , Sarah B Kingan , Zahra Mobasher , Maya Metni Pilkington , Michael F Hammer

DOI: 10.1038/NG1428

关键词:

摘要: Global-scale patterns of human population structure may be influenced by the rate migration among populations that is nearly eight times higher for females than males. This difference attributed mainly to widespread practice patrilocality, in which women move into their mates' residences after marriage1. Here we directly test this hypothesis comparing global DNA sequence variation on Y chromosome and mitochondrial (mtDNA) same panel 389 individuals from ten (four Africa two each Europe, Asia Oceania). We introduce a new strategy assay Y-chromosome identifies high density single-nucleotide polymorphisms, allows complete sequencing all rather relying predetermined markers provides direct comparisons with mtDNA. found overall proportion between-group (ΦST) 0.334 0.382 Genetic differentiation between was similar mtDNA at geographic scales tested. Although patrilocality important local scale2,3, genetic continental are not shaped

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