Pregnancy outcomes and impact of pregnancy on graft function in women after kidney transplantation.

摘要: Background Kidney transplantation facilitates pregnancy in women with end-stage kidney disease, however impact of on short and longer-term graft function is uncertain. Methods Obstetric, foetal outcomes for pregnancies from a large Australian transplant unit (1976-2015) were reviewed. Results There 56 35 mean age at conception 30.4±0.6 years transplant-pregnancy interval 5.5±0.5 years. The live birth rate (LBR) was 78.9%. Preterm ( 110umol/L had increased risk pre-eclampsia (OR 4.4; 95% CI 1.2-16.8; p=0.03), preterm 5.4; 0.5-53; p = 0.04) low birth-weight babies 1.2; 0.5-2.9; 0.04). Women SCr >140mol/L preconception worst trajectory, including higher rates loss. Conclusions KT remain high obstetric complications, particularly pre-eclampsia. Pre-pregnancy can be used to predict adverse deterioration during after delivery. This article protected by copyright. All rights reserved.