Needle biopsy findings in prostatic adenocarcinoma: experience at a tertiary care center in a developing country.

摘要: The objectives of this study are to report the findings in prostatic needle biopsies positive for cancer seen our practice with regard frequency detected at various sites, volume, Gleason grade, presence perineural invasion, and others; correlate volume serum prostate-specific antigen (PSA) levels; grade PSA levels. was conducted Section Histopathology, Department Pathology Microbiology, Aga Khan University Hospital, Karachi, Pakistan. All consecutive received from January 1, 2011 June 30, 2012, which were adenocarcinoma, included study. Statistical analysis carried out using SPSS 19.0 software package (SPSS Hong Kong Headquarters, Quarry Bay, Kong). A total 97 carcinoma period included. Prostate-specific levels available 60.8% cases ranged 5.0 1747 ng/mL. Tumor bilaterally present 54.6% cases. positivity right apex, mid, base 52.6%, 54.6%, 51.5%, respectively. left 55.7%, 63.9%, 59.8%, Average tumor 51.2%, 50.6%, 49.9%, 49.8%, 49.1%, 51.6%, score 6 52.6% 7 28.9% Perineural invasion 46.4% High-grade intraepithelial neoplasia 4 (4.1%) On statistical analysis, no significant correlation found between However, invasion. No level. To knowledge, these first reported Most carcinomas country still diagnosed on transurethral resection specimens, quite uncommon. Findings will help predicting adverse prognostic factors radical prostatectomies planning surgery accordingly.