Febre amarela silvestre: reemergência de transmissão no estado de São Paulo, Brasil, 2009

摘要: OBJECTIVE To describe the investigation of a sylvatic yellow fever outbreak in state Sao Paulo and main control measures undertaken. METHODS This is descriptive study Southwestern region from February to April 2009. Suspected confirmed cases humans non-human primates were evaluated. Entomological environment involved capture at ground level tree canopy identify species detect natural infections. Control performed urban areas Aedes aegypti . Vaccination was directed residents living with viral circulation also nearby cities according national recommendation. RESULTS Twenty-eight human (39.3% case fatality rate) rural Sarutaia, Piraju, Tejupa, Avare Buri. The deaths 56 reported, 91.4% Allouatta sp. Epizootics two Itapetininga A total 1,782 mosquitoes collected, including Haemagogus leucocelaenus , Hg. janthinomys/capricornii Sabethes chloropterus, Sa. purpureus undosus Yellow virus isolated group Leucocelaenus carried out 49 cities, 1,018,705 doses. Nine serious post-vaccination adverse events reported. CONCLUSIONS occurred between 2009 no recorded over 60 years. outside original recommended vaccination area high percentage susceptible population. fast adoption interrupted transmission within month confirmation humans, monkeys mosquitoes. results allowed identification new but further studies are required clarify dynamics spread this disease.