Beta-Thalassemia in Iran: New Insight into the Role of Genetic Admixture and Migration
作者： Ali Reza Rezaee , Mohammad Mehdi Banoei , Elham Khalili , Massoud Houshmand , None
DOI: 10.1100/2012/635183
关键词:
摘要: Iran with an area of 1.648 million km2 is located between the Caspian Sea and Persian Gulf. The Iranian population consists multiethnic groups that have been influenced by various invasions migration throughout history. Studies revealed presence more than 47 different β-globin gene mutations responsible for β-Thalassemia in Iran. This paper attempt to study origin parts Distribution shows patterns areas. a reflection people correlation ancestors. We compared frequencies regions those derived from neighboring countries. analysis provided evidence complementary information about genetic admixture some mutations, as well remarkable classification ethnic groups.
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