Supplementation with Tomato- Based Products Increases Lycopene, Phytofluene, and Phytoene Levels in Human Serum and Protects Against UV-light-induced Erythema

摘要: Carotenoids are suitable photoprotectants, and beta-carotene supplements used for protection against ultraviolet (UV) light-induced erythema. Protective effects also observed when carotenoids provided with the diet. Here, we investigated photoprotective of synthetic lycopene in comparison a tomato extract (Lyc-o-Mato) drink containing solubilized Lyc-o-Mato (Lyc-o-Guard-Drink). With these different sources, volunteers ingested similar amounts (about 10 mg/day). After 12 weeks supplementation, significant increases serum levels total skin were all groups. Significant phytofluene phytoene occurred Lyc-o-Guard-Drink group. At 0, 4, an erythema was induced solar light simulator. Dorsal each subject irradiated 1.25 minimal erythemal dose (MED). Reddening evaluated before 24 hours after irradiation by chromametry expressed as positive a-values (red/green-axis). delta (difference a-value hours) index intensity. A decrease from week 0 to 12, indicating prevention formation, Compared at 25% lower The protective effect more pronounced (38%) (48%) In two latter groups, may have contributed protection. Both exhibit absorption maxima wavelengths UV light. Absorption protects photodamage might explain differences between