BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module
作者： Daeho Park , Annie-Carole Tosello-Trampont , Michael R. Elliott , Mingjian Lu , Lisa B. Haney
DOI: 10.1038/NATURE06329
关键词:
摘要: Apoptotic cells must be removed by phagocytes to avoid local inflammation. They expose phosphatidylserine, which is normally restricted the inner leaflet of plasma membrane, on their surface, acting as an 'eat-me' signal. This paper shows that BAI1 protein upstream receptor for phosphatidylserine in mammalian macrophages
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Mingjian Lu, Kodi S. Ravichandran, Dock180–ELMO Cooperation in Rac Activation Methods in Enzymology. ,vol. 406, pp. 388- 402 ,(2006) , 10.1016/S0076-6879(06)06028-9
V A Fadok, D R Voelker, P M Henson, J J Cohen, P A Campbell, D L Bratton, Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. Journal of Immunology. ,vol. 148, pp. 2207- 2216 ,(1992)
Thóra K. Bjarnadóttir, Robert Fredriksson, Pär J. Höglund, David E. Gloriam, Malin C. Lagerström, Helgi B. Schiöth, The human and mouse repertoire of the adhesion family of G-protein-coupled receptors. Genomics. ,vol. 84, pp. 23- 33 ,(2004) , 10.1016/J.YGENO.2003.12.004
Peter M. Henson, Engulfment: ingestion and migration with Rac, Rho and TRIO. Current Biology. ,vol. 15, ,(2005) , 10.1016/J.CUB.2004.12.017
Yi Wu, Nitu Tibrewal, Raymond B. Birge, Phosphatidylserine recognition by phagocytes: a view to a kill Trends in Cell Biology. ,vol. 16, pp. 189- 197 ,(2006) , 10.1016/J.TCB.2006.02.003
Peter M. Henson, David A. Hume, Apoptotic cell removal in development and tissue homeostasis Trends in Immunology. ,vol. 27, pp. 244- 250 ,(2006) , 10.1016/J.IT.2006.03.005
Mingjian Lu, Jason M Kinchen, Kent L Rossman, Cynthia Grimsley, Colin deBakker, Enrico Brugnera, Annie-Carole Tosello-Trampont, Lisa B Haney, Doris Klingele, John Sondek, Michael O Hengartner, Kodi S Ravichandran, PH domain of ELMO functions in trans to regulate Rac activation via Dock180 Nature Structural & Molecular Biology. ,vol. 11, pp. 756- 762 ,(2004) , 10.1038/NSMB800
Robert S. Kiss, Michael R. Elliott, Zhong Ma, Yves L. Marcel, Kodi S. Ravichandran, Apoptotic Cells Induce a Phosphatidylserine-Dependent Homeostatic Response from Phagocytes Current Biology. ,vol. 16, pp. 2252- 2258 ,(2006) , 10.1016/J.CUB.2006.09.043
Balveen Kaur, Daniel J Brat, Narra S Devi, Erwin G Van Meir, None, Vasculostatin, a proteolytic fragment of brain angiogenesis inhibitor 1, is an antiangiogenic and antitumorigenic factor. Oncogene. ,vol. 24, pp. 3632- 3642 ,(2005) , 10.1038/SJ.ONC.1208317
N. H. Guo, H. C. Krutzsch, E. Negre, T. Vogel, D. A. Blake, D. D. Roberts, Heparin- and sulfatide-binding peptides from the type I repeats of human thrombospondin promote melanoma cell adhesion. Proceedings of the National Academy of Sciences. ,vol. 89, pp. 3040- 3044 ,(1992) , 10.1073/PNAS.89.7.3040