Pathogenic mechanisms of Bartonella quintana.

摘要: Bartonella quintana is an epi- and intracellular gram-negative rod responsible for both acute chronic clinical manifestations. We review the literature about pathogenic mechanisms of B. discuss our data. Our efforts to clarify pathogenesis run on two parallel tracks. The first one concerns interactions between endothelial cells by evaluation modulation apoptosis, signal transduction pathways inflammation. second some biological activities endotoxin human whole blood endothelium. elucidation regulating inflammatory/proliferative pattern manifestations infections may offer a contribution addressing bacterial persistence.