Multi-syringe flow injection solid-phase extraction system for on-line simultaneous spectrophotometric determination of nitro-substituted phenol isomers

摘要: Abstract In this paper, a time-based multi-syringe flow injection (MSFI) approach is proposed for automated disk-based sorbent extraction of three nitro-substituted phenol isomers (2-, 3-, and 4-nitrophenol) followed by on-line simultaneous determination individual species diode-array spectrophotometry. The method involves the enrichment targeted analytes from an acidic medium containing 0.1 mol L −1 HCl onto co-polymeric material, concurrent removal potentially interfering matrix components. nitrophenol are subsequently eluted with alkaline solution (0.7 mol L NaOH), whereupon eluate delivered to spectrophotometer recording spectral data in UV–vis region. Deconvolution strongly overlapped spectra was conducted multivariate regression models based on multiple linear calibration. analytical performance chemometric algorithm characterized relative prediction errors recoveries. MSFI manifold coupled multiposition selection valve set rugged analyzer that ensures minimum operational maintenance via exploitation membrane switching protocols. As compared earlier methods isolation/pre-concentration phenols liquid–liquid extraction, flow-through system should be regarded as environmentally friendly because use harmful organic solvents circumvented. Under optimized chemical physical variables, 3 σ blank detection limits 2-, 4-nitrophenol were 1.2, 3.2 0.3 μmol L sample loading volume 1.5 mL, standard deviations ≤5.0%. flowing system, which able handle up 135 samples automatically, proven suitable monitoring trace levels target mineral, tap, seawater.