Urinary bisphenol A detection is significantly associated with young and obese Thai children

摘要: Background: Bisphenol A (BPA), a xenoestrogenic monomer, is one of the most common industrial chemicals used in epoxy coatings for canned food and other consumer items. There only limited information regarding potential health risks from BPA exposure children adolescents Asian countries. Objective: To detect determine urinary concentrations, identify possible association between levels, demographic characteristics, Thai adolescents. Methods: cross-sectional study was conducted 376 aged 3−18 years kindergarten, elementary, middle schools Bangkok, Thailand. Urinary concentrations total were determined by liquid chromatography tandem mass spectrometry (LC−MSMS). Anthropometric data questionnaires collected. Results: detected 283 urine samples (75.3%) with median adjusted 0.53 μg/g creatinine (range 0.04−1.12). Thirty-one participants (9%) overweight 39 (11%) obese. The detection rate significantly higher obese (OR 3.42, 95% confidence interval (CI) 1.18−9.95, P = 0.02) compared normal weight. more often younger (3–6 years) when (6−10 (10−18 years). no significant levels or risks. Conclusions: may be lower than United States, some European nations, Obese associated detection.