Relation between procedural activated coagulation time and outcome after percutaneous transluminal coronary angioplasty

摘要: Objectives. The purpose of this study was to determine whether a low procedural activated coagulation time is associated with high rate in-hospital complications and identify there an range that may be complications. Background. In recent years the has come into widespread use for monitoring anticoagulation in catheterization laboratory. However, considerable controversy exists as standards by which judge “adequate” interventional procedures. Methods. From total 1,469 consecutive patients percutaneous transluminal coronary angioplasty, we retrospectively identified 103 (Group I, 7% overall population) major death or emergency urgent artery bypass graft surgery compared them 400 without II). Group I had more risk clinical characteristics, such type B C lesions, class III IV angina, myocardial infarction thrombolytic treatment. Activated times were between Groups II at baseline, after administration 10,000 U heparin end procedure. Results. There no differences baseline II. significantly lower therapy procedure: 61% 300 s; 279 27% s (p s. Conclusions. A diminished response initial bolus although did have higher before procedure. It remains determined ideal “target” procedures.