Capmatinib in MET Exon 14–Mutated or MET-Amplified Non–Small-Cell Lung Cancer

作者: Jürgen Wolf , Takashi Seto , Ji-Youn Han , Noemi Reguart , Edward B. Garon

DOI: 10.1056/NEJMOA2002787

关键词:

摘要: BACKGROUND Among patients with non-small-cell lung cancer (NSCLC), MET exon 14 skipping mutations occur in 3 to 4% and MET amplifications occur in 1 to 6%. Capmatinib, a …

参考文章(19)
A. Ali, J.R. Goffin, A. Arnold, P.M. Ellis, Survival of patients with non-small-cell lung cancer after a diagnosis of brain metastases. Current Oncology. ,vol. 20, pp. 300- 306 ,(2013) , 10.3747/CO.20.1481
Roderick J. Little, Ralph D'Agostino, Michael L. Cohen, Kay Dickersin, Scott S. Emerson, John T. Farrar, Constantine Frangakis, Joseph W. Hogan, Geert Molenberghs, Susan A. Murphy, James D. Neaton, Andrea Rotnitzky, Daniel Scharfstein, Weichung J. Shih, Jay P. Siegel, Hal Stern, The Prevention and Treatment of Missing Data in Clinical Trials The New England Journal of Medicine. ,vol. 367, pp. 1355- 1360 ,(2012) , 10.1056/NEJMSR1203730
E.A. Eisenhauer, P. Therasse, J. Bogaerts, L.H. Schwartz, D. Sargent, R. Ford, J. Dancey, S. Arbuck, S. Gwyther, M. Mooney, L. Rubinstein, L. Shankar, L. Dodd, R. Kaplan, D. Lacombe, J. Verweij, New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1) European Journal of Cancer. ,vol. 45, pp. 228- 247 ,(2009) , 10.1016/J.EJCA.2008.10.026
Ryoichi Onozato, Takayuki Kosaka, Hiroyuki Kuwano, Yoshitaka Sekido, Yasushi Yatabe, Tetsuya Mitsudomi, Activation of MET by Gene Amplification or by Splice Mutations Deleting the Juxtamembrane Domain in Primary Resected Lung Cancers Journal of Thoracic Oncology. ,vol. 4, pp. 5- 11 ,(2009) , 10.1097/JTO.0B013E3181913E0E
Benjamin J Solomon, Tony Mok, Dong-Wan Kim, Yi-Long Wu, Kazuhiko Nakagawa, Tarek Mekhail, Enriqueta Felip, Federico Cappuzzo, Jolanda Paolini, Tiziana Usari, Shrividya Iyer, Arlene Reisman, Keith D Wilner, Jennifer Tursi, Fiona Blackhall, None, First-line crizotinib versus chemotherapy in ALK-positive lung cancer The New England Journal of Medicine. ,vol. 371, pp. 2167- 2177 ,(2014) , 10.1056/NEJMOA1408440
Giorgio Vittorio Scagliotti, Purvish Parikh, Joachim von Pawel, Bonne Biesma, Johan Vansteenkiste, Christian Manegold, Piotr Serwatowski, Ulrich Gatzemeier, Raghunadharao Digumarti, Mauro Zukin, Jin S. Lee, Anders Mellemgaard, Keunchil Park, Shehkar Patil, Janusz Rolski, Tuncay Goksel, Filippo de Marinis, Lorinda Simms, Katherine P. Sugarman, David Gandara, Phase III Study Comparing Cisplatin Plus Gemcitabine With Cisplatin Plus Pemetrexed in Chemotherapy-Naive Patients With Advanced-Stage Non–Small-Cell Lung Cancer Journal of Clinical Oncology. ,vol. 26, pp. 3543- 3551 ,(2008) , 10.1200/JCO.2007.15.0375
Hossein Borghaei, Luis Paz-Ares, Leora Horn, David R Spigel, Martin Steins, Neal E Ready, Laura Q Chow, Everett E Vokes, Enriqueta Felip, Esther Holgado, Fabrice Barlesi, Martin Kohlhäufl, Oscar Arrieta, Marco Angelo Burgio, Jérôme Fayette, Hervé Lena, Elena Poddubskaya, David E Gerber, Scott N Gettinger, Charles M Rudin, Naiyer Rizvi, Lucio Crinò, George R Blumenschein Jr, Scott J Antonia, Cécile Dorange, Christopher T Harbison, Friedrich Graf Finckenstein, Julie R Brahmer, None, Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer The New England Journal of Medicine. ,vol. 373, pp. 1627- 1639 ,(2015) , 10.1056/NEJMOA1507643
Hans-Ulrich Schildhaus, Anne M. Schultheis, Josef Rüschoff, Elke Binot, Sabine Merkelbach-Bruse, Jana Fassunke, Wolfgang Schulte, Yon-Dschun Ko, Andreas Schlesinger, Marc Bos, Masyar Gardizi, Walburga Engel-Riedel, Michael Brockmann, Monika Serke, Ulrich Gerigk, Khosro Hekmat, Konrad F. Frank, Marcel Reiser, Holger Schulz, Stefan Krüger, Erich Stoelben, Thomas Zander, Jürgen Wolf, Reinhard Buettner, MET amplification status in therapy-naïve adeno- and squamous cell carcinomas of the lung Clinical Cancer Research. ,vol. 21, pp. 907- 915 ,(2015) , 10.1158/1078-0432.CCR-14-0450
Julie Brahmer, Karen L Reckamp, Paul Baas, Lucio Crinò, Wilfried EE Eberhardt, Elena Poddubskaya, Scott Antonia, Adam Pluzanski, Everett E Vokes, Esther Holgado, David Waterhouse, Neal Ready, Justin Gainor, Osvaldo Arén Frontera, Libor Havel, Martin Steins, Marina C Garassino, Joachim G Aerts, Manuel Domine, Luis Paz-Ares, Martin Reck, Christine Baudelet, Christopher T Harbison, Brian Lestini, David R Spigel, None, Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer The New England Journal of Medicine. ,vol. 373, pp. 123- 135 ,(2015) , 10.1056/NEJMOA1504627