EFFECTS OF COMBINED PANCREATIC AND RENAL TRANSPLANTATION ON DIABETIC NEUROPATHY: A TWO-YEAR FOLLOW-UP STUDY

作者: Göran Solders , Rolf Gunnarsson , Anders Persson , Henryk Wilczek , Gunnar Tydén

DOI: 10.1016/S0140-6736(87)91851-4

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摘要: To investigate whether diabetic neuropathy can be reversed after pancreatic transplantation 13 patients were examined by means of conventional electroneurography and tests on autonomic function before 6, 12, 24 months combined renal transplantation. 15 receiving a kidney graft only non-diabetic recipients served as controls. Before was most advanced in the two groups. Both groups showed similar slight but significant improvement nerve conduction In group became essentially normal. No dysfunction. The pancreas probably due to elimination uraemia. Furthermore, 2 years normoglycaemia did not reverse an important extent at this late stage disease.

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