Water-soluble AIE luminogen for monitoring and retardation of amyloid fibrillation of insulin
作者： Benzhong Tang , Yuning Hong , Ryan Tsz Kin Kwok , Sijie Chen
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摘要: The presently described subject matter is directed to a water-soluble conjugated polyene compound and the derivatives thereof that exhibit aggregation induced emission, as well any water dispersible, fluorescent, polymeric microparticles, nanoparticles, and/or pharmaceutical composition comprising thereof. Also provided are methods of making using compound, particles matter. useful bioprobes for detection biomacromolecules, in manufacture sensors, monitoring retarding formation amyloid protein fibril vitro vivo, developing anti-cancer drugs.
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